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. 2019 Oct 28;81(12):1753–1762. doi: 10.1292/jvms.19-0399

Table 2. Histopathological lung lesion scores at different intervals in group A and B mice after challenge with wild H3N8 equine influenza virus.

Days post challenge Cellular infiltrations Interstitial lesions Necrotic changes Total histopathological lesion




Group A Group B Group A Group B Group A Group B Group A Group B
1 1.17 ± 0.31c) 2.33 ± 0.21 1 ± 0.25 1.83 ± 0.31 0.17 ± 0.17b) 1.67 ± 0.42 1.33 ± 0.21c) 2.33 ± 0.21
3 1.5 ± 0.34b) 2.83 ± 0.31 1.5 ± 0.34a) 3.17 ± 0.31 0.67 ± 0.49a) 3 ± 0.26 1.5 ± 0.22a) 3.17 ± 0.17
5 1.67 ± 0.22 2.67 ± 0.22 1.33 ± 0.21b) 2.83 ± 0.17 0.67 ± 0.42 1.67 ± 0.56 1.67 ± 0.21a) 3 ± 0.26
9 1.17 ± 0.31c) 2.33 ± 0.21 1.17 ± 0.31c) 2.5 ± 0.43 0.33 ± 0.21 1.17 ± 0.54 1.17 ± 0.17 2 ± 0.26
14 0.83 ± 0.17 1.83 ± 0.40 0.17 ± 0.17c) 1.67 ± 0.49 0.17 ± 0.17 0.5 ± 0.34 0.5 ± 0.34 1.33 ± 0.42
28 0.83 ± 0.17 1 ± 0.37 0 ± 0 0.33 ± 0.21 0 ± 0 0 ± 0 0.17 ± 0.17 0.33 ± 0.21

Each value represents mean ± SEM (n=6). a) Indicates significant difference P<0.001, b) P<0.01, c) P<0.05, between groups in the same row in two way ANOVA, Bonnferoni post hoc test.