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. Author manuscript; available in PMC: 2020 Jan 6.
Published in final edited form as: Cell Physiol Biochem. 2019;52(5):1178–1192. doi: 10.33594/000000080

Fig. 5.

Fig. 5.

Helios is more closely associated with disease activity than Foxp3 on CD4+CD25hi T cells in RA patients. (a) The expression of Helios in CD4+CD25hi T cells was similar to Foxp3 on RA Tregs (p>0.05). (b) The expression of Helios in CD4+CD25hi T cells was negatively correlated with DAS28 score (r=−0.3277, p=0.0044) (left), while the expression of Foxp3 was not associated with DAS28 score on these T cells (p>0.05) (right). The p value was measured with Mann-Whitney test. Correlation analyses were carried out using Spearman’s rank correlation test. n.s., not significant.