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RV-59 inhibits cell growth of NLS-mutated Nrf2-transfected shNrf2-HCT116 stable clones. A. shNrf2-HCT116 stable clones and NLS-mutated Nrf2 shNrf2-HCT116 stable clones were treated with 19 novel drugs (10 μM) for 24 h, and the cell viability was evaluated by the MTT assay. B. Chemical structure of RV-59.
