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The IC50 value of shNRf2-HCT116 and NLS-mutated Nrf2-transfected shNrf2-HCT116 stable clones after treatment of 5-FU or RV-59. A. Both stable clones were treated with five concentrations of 5-FU for 48 h and the IC50 value for both clones were calculated from their dose-response survival curves. B. Both stable clones were treated with five concentrations of RV59 for 48 h and the IC50 value for both clones were calculated from their dose-response survival curves.
