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MEF2D promotes the migration, invasiveness, and EMT of HCC cells. SMMC-7721 and HCC-LM3 cells were infected with a lentivirus expressing shCtrl or shMEF2D. Cell migration (A) and invasion (B) are shown. Quantitative analysis revealed significantly weaker cell migration and invasion after the MEF2D knockdown. Scale bar, 100 μm. (C) The mRNA levels of E-cadherin, Vimentin and Slug. (D) Protein amounts of E-cadherin, Vimentin and Slug. *P < 0.05, **P < 0.01.
