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. 2019 Dec 27;7(2):e656. doi: 10.1212/NXI.0000000000000656

Figure 3. HLA-DRB1 colocalization in MS cortical gray matter.

Figure 3

Immunofluorescent colocalization of HLA-DRB1 with cellular markers for resident cells of the cortical gray matter. HLA-DRB1 colocalized with CD68, a marker for microglia (A, arrows). No colocalization with astrocytes (B, GFAP, arrowhead), neurons (C, NeuN, arrowhead), oligodendrocytes (D, OLIG2, arrowhead), and blood vessels (E, CD34, arrowhead) could be found. Scale bar: 50 μm. GFAP = glial-fibrillary acidic protein; NeuN = neuronal nuclei; OLIG2 = oligodendrocyte transcription factor 2.