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Effects of unsaponifiable matter (USM) from perilla seed meal on cytotoxicity (A), protective activity (B), total collagen production without UVB irradiation (C), and total collagen production with UVB irradiation (D) in Hs68 cells. UVB, ultraviolet b. Each value is expressed as the mean ± standard error (n = 3). Significance was tested using Tukey’s test. ### p < 0.001 versus the non-irradiated control. * p < 0.05 and *** p < 0.001 versus the UVB-irradiated control.
