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The effect of irisin on inflammation. (A) Human vcWAT and (B) scWAT were treated with or without irisin (50 nM) for 4 days, and the mRNA expression of pro-inflammatory (IL-6, TNFα, MCP-1, and MIP-1α) and anti-inflammatory (IL-10) genes were determined by qRT-PCR. Data are expressed as mean ± SEM; *P<0.05, **P<0.01 and ***P<0.001 statistical differenced compared to control.
