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. 2019 Dec 15;11(12):7385–7397.

Figure 1.

Figure 1

In colonic mucosal tissues of PI-IBS patients, miR-510 was downregulated, and PRDX1 was upregulated. A. Significant downregulation of miR-510 was observed in PI-IBS colonic mucosal tissues by qRT-PCR (left panel). B, C, G. Dramatic upregulation of the PRDX1 mRNA and proteins was observed in PI-IBS patients by qRT-PCR, Western blot (left panel) and Immunohistochemistry. D. Expression levels of PRDX1 were negatively correlated with miR-510 expression in the PI-IBS group. E. ELISA showed that the expression level of miR-510 was negatively correlated with serum TNF-α expression in the PI-IBS group. F. ELISA showed that the expression level of PRDX1 was positively correlated with serum TNF-α expression in the PI-IBS group. *P<0.05.