Figure 4.

Inflammatory injury induced by LPS in Caco-2 cells depends on the pro-inflammatory factor PRDX1. Silencing of PRDX1 alleviates the inflammatory injury induced by LPS. (A) Cell viability was increased dramatically. (B) Cell apoptosis and (C) mRNA expression of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6, and IL-8) were significantly decreased, and (D) the pro-inflammatory cytokine concentrations in the supernatant of cell culture were decreased significantly. **: P<0.01, ***: P<0.001.