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MiR-510 inhibition increased LPS-induced inflammatory injury in Caco-2 cells via PRDX1 overexpression. MiR-510 inhibitor or si-PRDX1 was transfected into Caco-2 cells. (A) Cell viability, (B) cell apoptosis, and (C) mRNA expression of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6, and IL-8) were measured using qRT-PCR. The concentrations of (D) TNF-α, (E) IL-1β, (F) IL-6, and (G) IL-8 in the supernatant of cell culture medium were examined by ELISA. *: P<0.05, ***: P<0.001.
