Table 1.

Relationship between CDK1 protein expression and clinical parameters in THCA detected by in-house immunohistochemistry with tissue microarrays

Clinicopathological features		n	CDK1 expression
			Mean ± SD	t/F value	p value
Tissue	THCA	171	7.08 ± 0.109	29.331a	<0.001
	Non-cancer	87	1.10 ± 0.189
Age	<45	83	7.18 ± 1.27	0.934a	0.351
	≥45	88	6.98 ± 1.55
Gender	Male	54	7.04 ± 1.43	-0.243a	0.808
	Female	117	7.09 ± 1.43
Pathological stage I	Stage 1	84	7.07 ± 0.144	F=1.242b	0.296
	Stage 2	52	6.85 ± 0.203
	Stage 3	29	7.38 ± 0.245
	Stage 4	6	7.67 ± 1.085
Pathological stage II	Stage 1-2	136	6.99 ± 0.118	1.652a	0.100
	Stage 3-4	35	7.43 ± 0.267
Pathological T stage I	T1	14	6.86 ± 0.345	F=1.660b	0.178
	T2	95	6.91 ± 0.143
	T3	56	7.36 ± 0.175
	T4	6	7.67 ± 1.085
Pathological T stage II	T1-T2	109	6.90 ± 0.132	-2.180a	0.031
	T3-T4	62	7.39 ± 0.186
Pathological N stage	N0	129	7.01 ± 1.44	-1.101a	0.273
	N1	42	7.29 ± 1.37

^aStudent’s 2-sample independent t-test was applied.

^bOne-way analysis of variance (ANOVA) test was conducted.

THCA: thyroid cancer.