Table 3.
Grading of Fatty liver in obese subjects
| Fatty liver grading | Obese (41) | ||
|---|---|---|---|
|
| |||
| Obese non-diabetics (23) | Obese diabetics (18) | Correlation (R); P value | |
| (i) Inflammation | 11 (47.8%) | 11 (61.1%) | NS |
| No inflammation | - | - | |
| Minimal | 8 (34.7%) | 4 (22.2%) | |
| Mild | 2 (8.6%) | 7 (38.8%) | |
| Moderate | 1 (4.3%) | - | |
| Severe | - | - | |
| (ii) Hepatosteatosis | 10 (43.5%) | 15 (83.3%)** | R = 0.405; P = 0.010 |
| 0% | - | - | |
| 0-33% | 7 (30.4%) | 6 (33.3%) | |
| 33-66% | 3 (13%) | 3 (16.6%) | |
| 66-100% | - | 6 (33.3%) | |
| (iii) Fibrosis | 5 (21.7%) | 7 (38.9%) | NS |
| Portal fibrosis | 5 (21.7%) | 5 (27.7%) | |
| Periportal fibrosis | - | 1 (5.5%) | |
| Septal fibrosis | - | - | |
| Cirrhosis | - | 1 (5.5%) | |
Fatty liver grading was compared between obese non-diabetics and obese diabetics using Fisher’s exact test or Pearson’s χ2 for categorical variables. Inflammation in liver biopsy was categorized with no inflammation, minimal, mild, moderate and severe inflammation; hepatosteatosis was categorized as 0%, 0-33%, 33-66% and 66-100%; and fibrosis was categorized as portal, periportal and septal fibrosis and cirrhosis for classification. Data show number of subjects in respective group (% subjects).
**
P < 0.01.