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. 2019 Nov 22;8(12):579. doi: 10.3390/antiox8120579

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of rosmarinic acid and sinapic acid on the oxidative damage markers level in the cardiac tissue of the HFD + STZ-induced type 2 diabetic rats. The results presented as mean ± SEM were evaluated by one−way ANOVA followed by LSD post-hoc test (statistically significant if p < 0.05). Values which have the same superscript letter(s) in each graph are not significantly different. When no letters are present in the superscript, the ANOVA test was not significant. C: control rats; DM2: HFD + STZ-induced diabetic rats; RA10 and RA50: HFD + STZ-induced diabetic rats treated with rosmarinic acid at a dose of 10 mg/kg and 50 mg/kg, respectively; SA5 and SA25: HFD + STZ-induced diabetic rats treated with sinapic acid at a dose of 5 mg/kg and 25 mg/kg, respectively, for 28 days; HFD: high-fat diet; STZ: streptozotocin; TBARS: thiobarbituric acid reactive substances.