Table A1.
Effect of rosmarinic acid and sinapic acid on the vital organ mass in HFD + STZ-induced type 2 diabetic rats.
Parameter | C | DM2 | RA10 | RA50 | SA5 | SA25 |
---|---|---|---|---|---|---|
Heart mass (g) | 0.607 ± 0.014 c | 0.662 ± 0.017 a,b | 0.639 ± 0.013 b,c | 0.628 ± 0.009bc | 0.645 ± 0.016 a,b,c | 0.694 ± 0.030 a |
Liver mass (g) | 5.972 ± 0.204 b | 7.178 ± 0.245 a | 7.107 ± 0.181 a | 6.695 ± 0.247a | 7.069 ± 0.197 a | 6.810 ± 0.139 a |
Kidney mass (g) | 0.764 ± 0.022 c | 0.822 ± 0.032 a,bc | 0.854 ± 0.015 a,b | 0.823 ± 0.039 a,b,c | 0.886 ± 0.028 a | 0.802 ± 0.012 b,c |
Uterus mass (g) | 0.425 ± 0.039 | 0.290 ± 0.038 | 0.339 ± 0.045 | 0.455 ± 0.068 | 0.419 ± 0.075 | 0.459 ± 0.039 |
The results presented as mean ± SEM were evaluated by one-way ANOVA followed by LSD post-hoc test (statistically significant if p < 0.05). Values which have the same superscript letter(s) within each row are not significantly different. When no letters are present in the superscript, the ANOVA test was not significant. C: control rats; DM2: HFD + STZ-induced diabetic rats; RA10 and RA50: HFD + STZ-induced diabetic rats treated with rosmarinic acid at a dose of 10 mg/kg and 50 mg/kg, respectively; SA5 and SA25: HFD + STZ-induced diabetic rats treated with sinapic acid at a dose of 5 mg/kg and 25 mg/kg, respectively, for 28 days.