Table A3.

Effect of rosmarinic acid and sinapic acid on the oxidative stress-related parameters in the cardiac tissue of HFD + STZ-induced type 2 diabetic rats.

Parameter	C	DM2	RA10	RA50	SA5	SA25
GPx (nmol/min/mg of protein)	0.900 ± 0.055	1.298 ± 0.208	1.066 ± 0.051	1.048 ± 0.047	1.175 ± 0.047	1.070 ± 0.075
NPSH (nmol/g of tissue)	19.50 ± 2.09	19.08 ± 2.53	29.53 ± 5.12	20.04 ± 5.09	29.14 ± 3.52	25.61 ± 4.83
AOPP (nmol/mg of protein)	27.87 ± 3.26	31.44 ± 5.94	27.77 ± 3.02	25.96 ± 3.25	24.87 ± 2.70	28.10 ± 2.10

The results presented as mean ± SEM were evaluated by one-way ANOVA followed by LSD post-hoc test (statistically significant if p < 0.05). Values which have the same superscript letter(s) within each row are not significantly different. When no letters are present in the superscript, the ANOVA test was not significant. C: control rats; DM2: HFD + STZ-induced diabetic rats; RA10 and RA50: HFD + STZ-induced diabetic rats treated with rosmarinic acid at a dose of 10 mg/kg and 50 mg/kg, respectively; SA5 and SA25: HFD + STZ-induced diabetic rats treated with sinapic acid at a dose of 5 mg/kg and 25 mg/kg, respectively, for 28 days; GPx: glutathione peroxidase; NPSH: non-protein sulfhydryl groups; AOPP: advanced oxidation protein products.