Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 15;24(24):4589. doi: 10.3390/molecules24244589

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Dynamics of CDK2 structure after binding of the compound 101874157. (A) Time evaluation of root-mean-square deviation (RMSD) of CDK2 and CDK2-101874157 complex. (B) Root-mean-square fluctuation (RMSF) of CDK2 before and after compound binding. (C) Time evolution of the radius of gyration. (D) Solvent accessible surface area (SASA) plot of CDK2 before and after compound binding. Values were obtained from the 50 ns molecular dynamics (MD) simulation time scale. Black and red represent free CDK2 and CDK2-101874157 complex, respectively.