Table 6.
Effects of stevioside supplementation on tight junction-related genes expression in the intestinal mucosae of LPS-challenged broilers.
| Treatments 2 | p value | |||||||
|---|---|---|---|---|---|---|---|---|
| Items 1 | CON | STE | LPS | LPS + STE | SEM | LPS | STE | Interaction |
| Jejunum | ||||||||
| CLDN1 | 1.00 | 0.86 | 0.75 | 0.95 | 0.08 | 0.324 | 0.701 | 0.055 |
| CLDN2 | 1.00 a | 0.76 a,b | 0.47 b | 0.68 a,b | 0.10 | 0.006 | 0.893 | 0.033 |
| OCLN | 1.00 a | 0.87 a,b | 0.70 b | 0.84 a,b | 0.06 | 0.023 | 0.751 | 0.030 |
| ZO-1 | 1.00 a | 0.94 a | 0.67 b | 1.04 a | 0.06 | 0.094 | 0.028 | 0.004 |
| Ileum | ||||||||
| CLDN1 | 1.00 | 1.02 | 0.96 | 1.06 | 0.12 | 0.996 | 0.644 | 0.772 |
| CLDN2 | 1.00 | 0.72 | 0.79 | 0.73 | 0.15 | 0.515 | 0.297 | 0.477 |
| OCLN | 1.00 | 0.98 | 0.64 | 0.87 | 0.07 | 0.010 | 0.217 | 0.131 |
| ZO-1 | 1.00 | 0.99 | 0.88 | 1.19 | 0.09 | 0.687 | 0.174 | 0.143 |
1CLDN1, claudin-1; CLDN2, claudin-2; OCLN, occludin; ZO-1, zonula occludens-1; 2 CON, non-challenged broilers fed a basal diet; STE, non-challenged broilers fed a basal diet supplemented with 250 mg/kg stevioside; LPS, LPS-challenged broilers fed a basal diet; LPS+STE, LPS-challenged broilers fed a basal diet supplemented with 250 mg/kg stevioside; SEM, standard error of mean; a,b Means (n = 6) with different letters within a row are significantly different (p < 0.05).