Table 7.
Effects of stevioside supplementation on intestinal mucosal oxidative status of LPS-challenged broilers.
| Treatments 2 | p value | |||||||
|---|---|---|---|---|---|---|---|---|
| Items 1 | CON | STE | LPS | LPS + STE | SEM | LPS | STE | Interaction |
| Jejunum | ||||||||
| MDA (nmol/mg protein) | 1.91 | 1.60 | 2.41 | 2.13 | 0.14 | 0.001 | 0.043 | 0.909 |
| T-AOC (mM/mg protein) | 56.53 a | 55.83 a,b | 45.96 b | 56.32 a | 2.61 | 0.243 | 0.021 | 0.012 |
| SOD (U/mg protein) | 35.54 | 35.03 | 27.72 | 36.74 | 2.10 | 0.219 | 0.092 | 0.062 |
| CAT (U/mg protein) | 3.45 | 4.37 | 2.49 | 3.27 | 0.39 | 0.016 | 0.043 | 0.856 |
| GSH-Px (U/mg protein) | 12.39 | 19.22 | 6.53 | 12.97 | 1.25 | <0.001 | <0.001 | 0.891 |
| Ileum | ||||||||
| MDA (nmol/mg protein) | 1.71 b | 1.67 b | 2.67 a | 1.90 b | 0.14 | 0.001 | 0.019 | 0.033 |
| T-AOC (mM/mg protein) | 46.62 | 44.46 | 33.99 | 40.54 | 2.33 | 0.002 | 0.365 | 0.088 |
| SOD (U/mg protein) | 22.02 a | 21.92 a | 16.91 b | 23.39 a | 1.15 | 0.136 | 0.014 | 0.011 |
| CAT (U/mg protein) | 3.24 | 3.13 | 2.61 | 2.65 | 0.15 | 0.002 | 0.824 | 0.630 |
| GSH-Px (U/mg protein) | 10.88 | 12.99 | 6.18 | 7.18 | 1.14 | <0.001 | 0.261 | 0.685 |
1 MDA, malondialdehyde; T-AOC, total antioxidant capacity; SOD, superoxide dismutase; CAT, catalase; GSH-Px, glutathione peroxidase; 2 CON, non-challenged broilers fed a basal diet; STE, non-challenged broilers fed a basal diet supplemented with 250 mg/kg stevioside; LPS, LPS-challenged broilers fed a basal diet; LPS+STE, LPS-challenged broilers fed a basal diet supplemented with 250 mg/kg stevioside; SEM, standard error of mean; a,b Means (n = 6) with different letters within a row are significantly different (p < 0.05).