Table 8.
Effects of stevioside supplementation on antioxidant gene expression in the intestinal mucosae of LPS-challenged broilers.
| Treatments 2 | p value | |||||||
|---|---|---|---|---|---|---|---|---|
| Items 1 | CON | STE | LPS | LPS + STE | SEM | LPS | STE | Interaction |
| Jejunum | ||||||||
| SOD1 | 1.00 | 1.19 | 0.76 | 0.98 | 0.06 | 0.001 | 0.002 | 0.739 |
| SOD2 | 1.00 a | 0.97 a | 0.71 b | 0.95 a | 0.05 | 0.019 | 0.029 | 0.008 |
| CAT | 1.00 | 1.10 | 0.60 | 0.88 | 0.07 | <0.001 | 0.012 | 0.211 |
| GPX1 | 1.00 | 1.38 | 0.61 | 1.05 | 0.13 | 0.020 | 0.009 | 0.795 |
| Nrf2 | 1.00 a | 0.99 a | 0.61 b | 0.95 a | 0.06 | 0.008 | 0.030 | 0.028 |
| HO-1 | 1.00 | 1.12 | 0.50 | 0.71 | 0.07 | <0.001 | 0.052 | 0.594 |
| Ileum | ||||||||
| SOD1 | 1.00 | 1.17 | 0.72 | 1.01 | 0.07 | 0.005 | 0.004 | 0.436 |
| SOD2 | 1.00 | 1.05 | 0.98 | 1.12 | 0.06 | 0.690 | 0.107 | 0.427 |
| CAT | 1.00 | 1.36 | 0.59 | 0.95 | 0.09 | <0.001 | <0.001 | 0.968 |
| GPX1 | 1.00 | 1.34 | 0.98 | 1.39 | 0.19 | 0.969 | 0.086 | 0.877 |
| Nrf2 | 1.00 | 1.34 | 0.94 | 1.30 | 0.15 | 0.745 | 0.040 | 0.946 |
| HO-1 | 1.00 | 1.34 | 0.45 | 0.88 | 0.08 | <0.001 | <0.001 | 0.593 |
1SOD1, superoxide dismutase-1; SOD2, superoxide dismutase-2; CAT, catalase; GPX1, glutathione peroxidase 1; Nrf2, nuclear factor-erythroid 2-related factor 2; HO-1, heme oxygenase-1; 2 CON, non-challenged broilers fed a basal diet; STE, non-challenged broilers fed a basal diet supplemented with 250 mg/kg stevioside; LPS, LPS-challenged broilers fed a basal diet; LPS + STE, LPS-challenged broilers fed a basal diet supplemented with 250 mg/kg stevioside; SEM, standard error of mean; a,b Means (n = 6) with different letters within a row are significantly different (p < 0.05).