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Time dependent changes of CSC related cell signaling genes and marker genes expression in HT29. The CSC enriched cultured cells were treated with evodiamine for 48 h or 72 h and the mRNA expressions were tested with quantitative RT-PCR. Only Notch1, LRP5, Jagged, CD133 and SCD1 showed similar expression changes in time dependent manner. * p < 0.05; ** p < 0.01; *** p < 0.001 vs. each controls.
