. 2019 Sep 19;5(1):66–80. doi: 10.1016/j.ekir.2019.09.009

Table 4.

Candidate protein biomarkers to predict or define molecular pathways/targets of steroid resistance in pediatric nephrotic syndrome

Protein	Name	Predictive biomarker^a		Defining biomarker^b
Protein	Name	Proteomics	IB^c	Proteomics	IB^c
COL6A3	Collagen alpha-3(VI) chain	X		X
IGFBP2	Insulin-like growth factor-binding protein 2	X		X
MMP2	72 kDa type IV collagenase	X		X	X
APOE	Apolipoprotein E	X
ADIPOQ	Adiponectin	X		X	X
SHBG	Sex hormone–binding globulin	X		X	X
EFEMP1	EGF-containing fibulin-like extracellular matrix protein 1	X		X
ITIH4	Inter-alpha-trypsin inhibitor heavy chain H4	X		X
HPX	Hemopexin	X		X	X
VDB	Vitamin D binding protein	X	X	X	X
SERPINC1	Antithrombin-III	X		X
AZGP1	Zinc-alpha-2-glycoprotein	X		X
FETUB	Fetuin-B	X		X
APOL1	Apolipoprotein L1		X	X	X

^a,b

Approaches defined in Figure 1.

Immunoblotting.