Fig. 5.

Moderate exercise-induced HIF-1α expression in the small intestine. (A) ODD-Luc mice were immediately anesthetized and sacrificed after a bout of 30 min of swimming, n = 3/group. Their abdominal cavity viscera were removed for bioluminescence imaging to detect HIF-1α expression. The small intestine generated a greater level of photons (arrows) than the colon, liver, and stomach. (B) The photon levels in the colon, small intestine, and liver of ODD-Luc mice were recorded after a moderate exercise bout, n = 3/group. **p < 0.01. The color bar indicates the photon level (cm²/s/steradian) and the minimum and maximum threshold values. CON = ODD-Luc mice were exposed to normoxic conditions; HIF = hypoxia-inducible factor; ODD = oxygen-dependent degradation domain.