Figure 3.

Web interface of PsyMuKB

A snapshot of the major functionalities of PsyMuKB using neuropsychiatric-related gene DYRK1A as an example. A. General information about DYRK1A, including description, summaries, and gene pathogenicity assessment. B. The information about the expression, associated regulated element, PPIs of DYRK1A. C. The mutation summary table of DYRK1A and the visualization of genomic locations of mutations in different transcripts. D. The interface for identifying the isoform-specific mutations of DYRK1A using the tissue-specific expression of isoforms and their exon–intron structure map. PPI, protein–protein interaction.