Figure 4.
These western/immune blots demonstrate the effect of mNPH CEM 30, 8 Gy and 8 Gy+mNPH had on various protein expression level, with GAPDH as a loading sample. Although mNPH and 8 Gy/mNPH had lower GAPDH than the other conditions, the amount of HSP70 protein was dramatically greater, as was p-mTOR. Additionally, p-MDM2 expression was very significantly decreased following hyperthermia and combinatorial treatments.