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. Author manuscript; available in PMC: 2020 Jan 6.
Published in final edited form as: Angew Chem Int Ed Engl. 2019 Jan 14;58(13):4112–4128. doi: 10.1002/anie.201807847

Figure 5.

Figure 5.

Dose effect on renal clearance of glutathione-coated gold nanoparticles (GS-AuNPs) with core size of 2.5 nm after intravenous injection. A) The renal clearance efficiency at 2 h post injection was independent of injected dose at a low-dose range from 0.15 to 15 mgkg−1, B) but it linearly increased from 34.6 to 69.0 percentage of injected dose (%ID) as dose increased from 15 to 1059 mgkg−1 (n =3 for each group; *P<0.05; ns, no significant difference, P> 0.05). Reproduced with permission from Ref. [58]. Copyright 2017, John Wiley and Sons.