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. Author manuscript; available in PMC: 2020 Jan 6.
Published in final edited form as: Angew Chem Int Ed Engl. 2019 Jan 14;58(13):4112–4128. doi: 10.1002/anie.201807847

Figure 6.

Figure 6.

Comparison of renal-clearable NIR-emitting IRDye 800CW and renal-clearable NIR-emitting GS-AuNPs in in vivo fluorescence kidney imaging. A) Whole-body images of mice were obtained invasively (skin above the kidney was surgically removed) and noninvasively (hair-removed skin was intact) before and after intravenous injection of IRDye 800CW (Ex/Em filters:710/790 nm) or C) GS-AuNPs (Ex/Em filters: 710/830 nm). LK=left kidney, RK =right kidney. B) Time-fluorescence intensity curves of the kidneys and skin obtained from invasive imaging after iv injection of GS-AuNPs and IRDye 800CW. D) Comparison of time-dependent kidney contrast enhancements in percentage after GS-AuNPs and IRDye 800CW injection, respectively (n = 3). Reproduced with permission from Ref. [65]. Copyright 2015, John Wiley and Sons.