Table 1.
Univariate and multivariate analyses of clinicopathological variables in relation to overall survival in patients undergoing potentially curative resection for gastric cancer
| Clinicopathological features | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age | 1.03 (1.02–1.04) | < 0.001 | 1.02 (1.01–1.03) | < 0.001 |
| Sex | 0.979 | |||
| Male | Reference | |||
| Female | 1.00 (0.83–1.21) | |||
| BMI | 0.94 (0.92–0.97) | < 0.001 | 0.058 | |
| ASA score | 0.013 | 0.740 | ||
| 1 | Reference | |||
| 2 | 1.29 (1.09–1.53) | |||
| 3 | 1.18 (0.75–1.86) | |||
| Tumor location | < 0.001 | < 0.001 | ||
| Upper | Reference | Reference | ||
| Middle | 1.05 (0.83–1.33) | 0.92 (0.72–1.17) | ||
| Lower | 0.59 (0.48–0.73) | 0.79 (0.64–0.97) | ||
| Mixed | 1.56 (1.22–1.98) | 1.32 (1.03–1.70) | ||
| Tumor size (cm) | 1.02 (1.01–1.02) | < 0.001 | 1.01 (1.00–1.01) | 0.003 |
| Histologic type | 0.069 | |||
| Differentiated | Reference | |||
| Undifferentiated | 1.22 (0.99–1.51) | |||
| Vascular invasion | < 0.001 | 0.655 | ||
| Negative | Reference | |||
| Positive | 1.69 (1.41–2.02) | |||
| Perineural invasion | < 0.001 | 0.885 | ||
| Negative | Reference | |||
| Positive | 1.63 (1.33–1.99) | |||
| pTNM stage | < 0.001 | < 0.001 | ||
| I | Reference | Reference | ||
| II | 2.65 (1.82–3.68) | 2.00 (1.38–2.90) | ||
| III | 9.74 (7.05–13.46) | 6.80 (4.91–9.41) | ||
| Adjuvant chemotherapy | 0.260 | |||
| No | Reference | |||
| Yes | 1.10 (0.93–1.31) | |||
| Hb | < 0.001 | 0.003 | ||
| < 125 | Reference | Reference | ||
| ≥ 125 | 0.51 (0.43–0.60) | 0.77 (0.65–0.91) | ||
| LMR | < 0.001 | 0.003 | ||
| < 3.4 | Reference | Reference | ||
| ≥ 3.4 | 0.59 (0.50–0.70) | 0.78 (0.65–0.91) | ||
| PLR | < 0.001 | 0.434 | ||
| < 161.3 | Reference | |||
| ≥ 161.3 | 1.70 (1.44–2.00) | |||