Table 3.
Multivariate analysis of the CBCS clinicopathological variables in relation to overall survival in patients undergoing potentially curative resection for gastric cancer
| Clinicopathological features | Multivariate analysis* | Internal validation* | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age | 1.02 (1.02–1.03) | < 0.001 | 1.02 (1.02–1.03) | < 0.001 |
| Tumor Location | < 0.001 | < 0.001 | ||
| Upper | Reference | Reference | ||
| Middle | 0.92 (0.72–1.17) | 0.91 (0.72–1.15) | ||
| Lower | 0.79 (0.64–0.97) | 0.78 (0.64–0.96) | ||
| Mixed | 1.32 (1.03–1.70) | 1.30 (1.02–1.66) | ||
| Tumor size (cm) | 1.01 (1.00–1.01) | 0.003 | 1.01 (1.00–1.01) | < 0.001 |
| pTNM stage | < 0.001 | < 0.001 | ||
| I | Reference | Reference | ||
| II | 2.00 (1.38–2.91) | 2.02 (1.42–2.88) | ||
| III | 6.81 (4.92–9.42) | 6.82 (4.97–9.36) | ||
| CBCS | < 0.001 | < 0.001 | ||
| 0 | Reference | Reference | ||
| 1 | 1.29 (1.06–1.57) | 1.27 (1.03–1.54) | ||
| 2 | 1.68 (1.35–2.09) | 1.60 (1.22–1.94) | ||
*Adjusted for the following variables: age, BMI, ASA score, tumor location, vascular invasion, perineural invasion, pTNM stage, CBCS, and PLR