Table 3.
CGMS results.
| Dulaglutide group (n = 16) | Glargine (n = 9) | t | p | ||
|---|---|---|---|---|---|
| PT2.8 | Baseline | 0 (0, 0) | 0 (0, 0) | 0 | 1 |
| 52w | 0 (0, 0) | 0 (0, 0.50) | −1.925 | 0.054 | |
| AUC2.8 | Baseline | 0 (0, 0) | 0 (0, 0) | 0 | 1 |
| 52w | 0 (0, 0) | 0 (0, 0) | −1.333 | 0.182 | |
| PT3.9 | Baseline | 0 (0, 0) | 0 (0, 0) | −0.15 | 0.88 |
| 52w | 0 (0, 0) | 0 (0, 8.00) | −0.446 | 0.656 | |
| AUC3.9 | Baseline | 0 (0, 0) | 0 (0, 0) | 0 | 1 |
| 52w | 0 (0, 0) | 0 (0, 0.05) | −1.925 | 0.054 | |
| PT3.9–7.8 | Baseline | 6.00 (0, 28.50) | 10.00 (1.00, 33.00) | −0.605 | 0.545 |
| 52w | 51.50 (27.00, 62.75) | 44.00 (22.50, 66.50) | −0.482 | 0.63 | |
| PT3.9–10 | Baseline | 35.50 (4.25, 49.75) | 36.00 (15.50, 53.50) | −0.34 | 0.734 |
| 52w | 80.50 (66.00, 91.75) | 56.00 (38.50, 86.50) | −1.359 | 0.174 | |
| PT10 | Baseline | 64.50 (49.50, 95.75) | 64.00 (46.50, 84.50) | −0.34 | 0.734 |
| 52w | 19.50 (8.00, 34.00) | 25.00 (11.50, 54.50) | −1.048 | 0.295 | |
| AUC10 | Baseline | 2.05 (1.23, 4.50) | 1.80 (1.05, 2.75) | −0.425 | 0.671 |
| 52w | 0.30 (0.10, 1.28) | 0.40 (0.10, 2.45) | −0.913 | 0.361 | |
| PT13.9 | Baseline | 25.00 (6.00, 41.25) | 18.00 (8.00, 36.50) | −0.425 | 0.671 |
| 52w | 0.50 (0, 11.50) | 0 (0, 29.50) | −0.427 | 0.669 | |
| AUC13.9 | Baseline | 0.30 (0.03, 1.58) | 0.30 (0.15, 0.45) | −0.23 | 0.818 |
| 52w | 0 (0, 0.18) | 0 (0, 0.65) | −0.513 | 0.608 | |
| MBG | Baseline | 11.93 ± 3.00 | 11.26 ± 2.08 | 0.598 | 0.556 |
| 52w | 8.63 ± 1.52 | 8.83 ± 2.00 | −0.285 | 0.778 | |
| SDBG | Baseline | 2.75 ± 0.65 | 2.67 ± 0.60 | 0.317 | 0.754 |
| 52w | 2.24 ± 0.95 | 2.91 ± 1.31 | −1.486 | 0.151 | |
| MAX | Baseline | 17.70 ± 2.92 | 17.18 ± 2.31 | 0.46 | 0.65 |
| 52w | 14.43 ± 3.47 | 15.14 ± 3.90 | -0.472 | 0.641 | |
| MIN | Baseline | 7.19 ± 2.70 | 6.43 ± 2.46 | 0.697 | 0.493 |
| 52w | 5.06 ± 1.21 | 4.46 ± 1.62 | 1.065 | 0.298 | |
| Change | −2.30 (−3.08, −0.15) | −2.60 (−4.15, 1.25) | −0.17 | 0.865 | |
| LAGE | Baseline | 10.52 ± 1.85 | 10.74 ± 1.85 | −0.29 | 0.775 |
| 52w | 8.98 ± 3.76 | 10.69 ± 3.86 | −1.078 | 0.292 | |
| MAGE | Baseline | 6.74 ± 1.99 | 6.88 ± 2.20 | −0.157 | 0.877 |
| 52w | 5.86 ± 2.81 | 7.09 ± 3.21 | −0.997 | 0.329 | |
| M-Value | Baseline | 26.76 (16.31, 58.85) | 24.80 (16.04, 34.97) | −0.481 | 0.63 |
| 52w | 5.19 (2.47, 14.96) | 10.75 (4.42, 33.65) | −1.585 | 0.113 | |
| MODD | Baseline | 2.33 ± 1.33 | 2.33 ± 0.83 | 0.002 | 0.999 |
| 52w | 1.91 ± 0.90 | 2.19 ± 0.62 | −0.82 | 0.424 |
PT: Percentage time of blood glucose; AUC: area under the curve; MBG, mean blood glucose; SDBG: standard deviation of blood glucose; MAX: the maximum blood glucose; MIN: the minimum blood glucose; LAGE: the largest amplitude of glycemic excursion; MAGE: mean amplitude of glycemic excursion; MODD: absolute means of daily difference.