Table 2.
OncoChase | Digital PCR | ||||||
---|---|---|---|---|---|---|---|
Gene | AA change | Sample ID | Sample type | VAF (%) | VAF (%) | CI (%) | |
KRAS | G12V | CRC-1 | Tumor | 74.2 | 74.4 | 70.3–78.8 | |
cfDNA | - | 1.6 | 0.9–3.0 | ||||
KRAS | G12C | CRC-2 | Tumor | 75.8 | 77.9 | 74.6–81.3 | |
cfDNA | - | 2.1 | 1.2–3.9 | ||||
KRAS | G13D | CRC-3 | Tumor | 40.9 | 36.7 | 35.1–38.5 | |
cfDNA | - | 0.2 | 8.6×10-2–0.3 |
PCR, polymerase chain reaction; AA, amino acid; VAF, variant allele frequency; CI, confidence interval; cfDNA, plasma cell–free DNA.