Figure 3. Discovery of candidate genes or molecules associated with SCI-TBI-HO by Open discovery methodology.

“Ossification, heterotopic (C0029396)” (X) was used to screen the concepts of “spinal cord injury or traumatic brain injury” related to Heterotopic Ossification. Then the Concepts (Y) was used to mining the associated “Gene or gene product.” Second, the drug target was used to filter the “Z” by taking the intersection of them (define as promising genes). Finally, the Human eFP Browser was used to filter the promising genes.