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. 2017 Dec;58(12):1991–1996. doi: 10.2967/jnumed.117.193532

FIGURE 2.

FIGURE 2.

(A) Metabolic stability of each probe estimated from HPLC analysis of serum samples in rat at 15 and 60 min after probe injection. (B) Mean whole lung PET activity values in sham and bleomycin-treated mice (2 wk after bleomycin instillation) for CBP1, CBP3, CBP5, CBP6, and CBP7 (100–120 min after injection). (C) Ex vivo lung uptake in sham and bleomycin-treated mice (2 wk after bleomycin instillation) for CBP1, CBP3, CBP5, CBP6, and CBP7 at 150 min after probe injection. ****P < 0.0001. BM = bleomycin.