Figure 6.

Developmental PCB153 exposure on altered circadian behavior. Zebrafish embryos were exposed to either 1 μM PCB153 or dimethyl sulfoxide (DMSO) control from 4 to 120 h post-fertilization and circadian behavior was assessed for 3 days starting from 6 days post-fertilization. A. Average locomotor activity (moving average of 10 sliding points) is plotted against circadian time. B. G-factor ratios, a determinant of the extent to which the observed locomotor behavior is circadian in nature is calculated for DMSO control and PCB153 exposed groups. The detailed data analysis steps are provided in the methods section. p-value of <.05 is considered statistically significant.