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. Author manuscript; available in PMC: 2020 Jan 6.
Published in final edited form as: Nat Rev Dis Primers. 2019 May 30;5(1):38. doi: 10.1038/s41572-019-0087-y

Fig. 5 |. Relationship between age, BMI and reproductive hormones.

Fig. 5 |

The graphs present mean levels of total and calculated free testosterone, luteinizing hormone (LH) and sex hormone-binding globulin (SHBC). a | Total testosterone is reduced in overweight and obese men compared with nonobese men at all ages. b | Free testosterone, similar to total testosterone, is reduced in overweight and obese men compared with nonobese men at all ages. c | LH increases with age but is not associated with body mass index (BMI). d | SHBC increases with age. For total testosterone and SHBC, no interaction between BMI and age were found, whereas free testosterone showed an interaction between BMI and age. The data were derived from a cohort of 3,220 men aged 40–79 years recruited in the European Male Ageing Study (EMAS) study. Shaded areas and vertical lines represent the 95% CI. Adapted with permission from REF.76, Oxford University Press.