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. 2019 Nov;7(22):646. doi: 10.21037/atm.2019.10.54

Figure 3.

Figure 3

High level of arm copy number alterations associates with worse survival and higher tumor mutation burden. (A) Number of arm SCNAs in early stage (I & II) and late stage (III & IV) ccRCC patients; (B) number of arm SCNAs in low grade (I & II) and high grade (III & IV) ccRCC patients; (C) tumor mutation burdens in arm SCNAhigh and SCNAlow tumors; (D) Kaplan-Meier analysis of arm SCNA level for OS in ccRCC patients; (E) Kaplan-Meier analysis of arm SCNA level for RFS in ccRCC patients. *, P<0.05; ***, P<0.001. SCNA, somatic copy number alteration; ccRCC, clear cell renal cell carcinoma.