Figure S1.

miR-3619-3p promotes papillary thyroid carcinoma progression. (A) qRT-PCR analysis of miR-3619-3p expression in NC, mimics, and inhibitor-treated PTC cells; (B,C) transwell migration and invasion assays for TPC-1 that were transfected with miR-3619-3p mimics or NC followed by treatment with ICG-001 (10 µm) for 24 h; (D,E) transwell migration and invasion assays for TPC-1 that were transfected with miR-3619-3p inhibitor or NC after treatment with LiCL (20 mM) for 24 h. (B,C,D,E) The cells were stained with 0.05% crystal violet. Representative images of migration and invasion are shown; all images were obtained at 100x magnification under an inverted microscope. The cells that had migrated were counted from ten randomly chosen fields. Error bars correspond to the mean ± SD of triplicate experiments. (F,G,H,I) Wound healing assays of TPC-1 after treatment, respectively. The data represented the mean ± SD from three independent experiments. **, P<0.01. PTC, papillary thyroid carcinoma; qRT-PCR, quantitative real-time polymerase chain reaction.