Table 3. Stratified analysis of the association that six SNPs with hypertension in the follow-up study.
| SNPs | Group | MM/Mm/mm | Additive model HR (95% CI) | Dominate model HR (95% CI) | Recessive model HR (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Crude | Adjusta | Crude | Adjusta | Crude | Adjusta | |||||
| rs2229202 | Men | 207/52/7 | 1.426 (1.097–1.854) P=0.008 |
1.448 (1.111–1.886) P=0.006 |
1.342 (1.003–1.795) P=0.048 |
1.372 (1.023–1.841) P=0.035 |
3.926 (1.848–8.343) P<0.001 |
3.729 (1.722–8.073) P=0.001 |
||
| Women | 284/59/4 | 0.944 (0.738–1.207) P=0.645 |
0.935 (0.726–1.204) P=0.601 |
0.955 (0.727–1.255) P=0.743 |
0.926 (0.702–1.221) P=0.585 |
0.739 (0.276–1.981) P=0.548 |
0.95 (0.353–2.56) P=0.919 |
|||
| rs2229202 | Non-smoking | 368/80/6 | 1.014 (0.821–1.252) P=0.899 |
0.989 (0.796–1.23) P=0.924 |
1.021 (0.807–1.291) P=0.863 |
0.972 (0.767–1.233) P=0.817 |
0.958 (0.428–2.144) P=0.916 |
1.218 (0.542–2.739) P=0.633 |
||
| Smoking | 123/31/5 | 1.504 (1.077–2.101) P=0.01 |
1.53 (1.099–2.131) P=0.012 |
1.393 (0.958–2.026) P=0.083 |
1.475 (1.009–2.157) P=0.045 |
4.625 (1.889–11.325) P=0.001 |
3.585 (1.414–9.09) P=0.007 |
|||
a, adjusted for age, gender, TC, TG, HDL-C, LDL-C, GLU, BMI, drinking and smoking. SNPs, single nucleotide polymorphisms; M, major allele; m, minor allele; HR, hazard ratio; CI, confidence interval; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; GLU, levels and glucose; BMI, body mass index.