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. 2019 Nov;7(22):660. doi: 10.21037/atm.2019.10.75

Table 2. Performance of variables in predicting 90-day mortality.

Variable AUC ROC 95% CI P Cut-off Sensitivity (%) Specificity (%)
APACHE II score 0.84±0.06 0.73–0.95 <0.001 ≥13.5 87.5 72.1
LDHday 1 0.78±0.06 0.66–0.90 <0.001 ≥375 75 63.3
LDHday 3 0.93±0.03 0.88–0.98 <0.001 ≥453 94 87
LDHc 0.85±0.06 0.73–0.97 <0.001 ≥9.2 75 90
PSI score 0.65±0.08 0.49–0.81 0.07 ≥109.5 68.8 48.3
CURB-65 0.64±0.09 0.47–0.81 0.09 ≥2.5 50 80

AUC ROC, area under the receiver operating characteristic curve; CI, confidence interval; APACHE-II, Acute Physiology and Chronic Health Evaluation II; PSI, Pneumonia Severity Index; LDHday1, LDH level at ICU admission; LDHday3, LDH level on day 3; LDHc, LDH change from day 1 to day 3 [calculated using the following formula: LDHc (%) = (LDHday3 – LDHday1)/LDHday1 ×100%].