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Score of the signatures of different responses of NCT identified before and after NCT (performed by PLS-DA) (A) Signatures of SD and PR patients both have great changes after chemotherapy, separately; (B) signatures of SD patients and PR patients classified obviously before NCT start; (C) signatures of SD patients and PR patients classified after NCT. NCT, neoadjuvant chemotherapy; PLS-DA, partial least squares discriminant analysis; SD, stable disease; PR, partial response.
