Table 5. Multivariable cox regression analyses of CSS in all patients.
Variables | HR | 95% CI lower | 95% CI upper | P value |
---|---|---|---|---|
Gender (male vs. female) | 0.885 | 0.690 | 1.135 | 0.337 |
Age | 1.001 | 0.991 | 1.010 | 0.873 |
Tumor location | ||||
Lower | Ref | Ref | Ref | Ref |
Middle | 1.032 | 0.773 | 1.377 | 0.832 |
Upper | 1.210 | 0.938 | 1.560 | 0.143 |
Tumor size (≥5 vs. <5 cm) | 1.427 | 1.133 | 1.798 | 0.003 |
Differentiated (high vs. low) | 1.571 | 1.228 | 2.010 | <0.001 |
Chemotherapy | 0.149 | 0.114 | 0.195 | <0.001 |
pT stage | ||||
pT1 | Ref | Ref | Ref | Ref |
pT2 | 1.527 | 0.723 | 3.224 | 0.267 |
pT3 | 3.971 | 1.994 | 7.909 | <0.001 |
pT4a | 4.251 | 2.154 | 8.388 | <0.001 |
pT4b | 6.831 | 3.360 | 13.891 | <0.001 |
pN stage | ||||
pN0 | Ref | Ref | Ref | Ref |
pN1 | 4.617 | 2.915 | 7.312 | <0.001 |
pN2 | 5.765 | 3.733 | 8.904 | <0.001 |
pN3a | 9.735 | 6.296 | 15.053 | <0.001 |
pN3b | 8.861 | 5.570 | 14.096 | <0.001 |
TD | 1.905 | 1.470 | 2.469 | <0.001 |
CSS, cancer-specific survival; HR, hazard ratio; CI, confidence interval; TD, tumor deposit.