Figure 2.

Mean and standard errors of CSF NFL levels of different diagnostic groups and genotypes. The minor allele of rs465401 (A) was associated with the increase in CSF NFL concentration among all diagnostic groups except CN with a multiple linear regression model, including age, gender, education and APOE ε4 as covariates. The p-values for the main effect of SNP were shown in each diagnostic group. CSF, cerebrospinal fluid; NFL, neurofilament light; CN, cognitively normal; MCI, mild cognitive impairment.