Fig. 3. miR-578 inhibits the growth and migration of osteosarcoma cells by targeting VEGF.
a The proliferation of cells expressing control, miR-578 or miR-578 inhibitor for 24 h was determined by MTT assay. b, c Migration of cells expressing control, miR-578 or miR-578 inhibitor was detected by the transwell assay. d–g The indicated proteins in cells expressing control, miR-578 or miR-578 inhibitor were detected by western blot and real-time PCR. Results represented the mean ± s.d. of independently repeated experiments. **P < 0.01, vs control. miR-578 in, miR-578 inhibitor.