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. 2020 Jan 6;11(1):18. doi: 10.1038/s41419-019-2204-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Proliferation in cells expressing control, circ_001621 or combination was detected by the MTT assay. b Migration of MG63 cells expressing control, circ_001621 or combination was detected by the transwell assay. The indicated genes expression in MG63 cells were detected by western blot (c) and real-time PCR (d), separately. Results represented the mean ± s.d. of three independent experiments. **P < 0.01, vs control, ^##P < 0.01, vs circ_001621. e Immunofluorescent stain of VEGF in the indicated MG63 cells. Green, VEGF; Blue, DAPI.