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. 2020 Jan 6;11(1):8. doi: 10.1038/s41419-019-2203-z

Fig. 2. BCL-XL is important for the survival of differentiating CD34+ cells.

Fig. 2

a–f Human HSPC were seeded in MethoCult medium. After 10 days of culture, colonies were identified (granulocyte-erythrocyte-megakaryocyte-monocyte precursors (GEMM), granulocytic–monocytic precursors (GM), granulocytes (G), erythroid (E), and monocyte precursors (M)) and counted by light microscopy (a). GFP expression was determined before and after culture (b). Several hematopoietic populations were analyzed by flow cytometry along with GFP expression (c, d) and cell numbers (e, f). Supplementary Table 2 shows the immunophenotype of the hematopoietic populations. Abbreviations: hematopoietic stem cells (HSC), multipotent progenitors (MPP), granulocytic–monocytic progenitors (GM), Colony Forming Unit granulocytes (CFU-G). Bars represent mean ± SEM, n = 8–9 from five independent experiments. p-values: b ****p < 0.0001. c **p = 0.0025, ***p = 0.001, ****p < 0.0001. d ****p < 0.0001. e *p = 0.036 for CD34+ cells, *p = 0.0274 for HSC. f **p = 0.0037.