Table 1.

Demographic data, clinical and HIV infection characteristics, and comorbidities of HIV participants, uninfected volunteers and Alzheimer’s disease

	HIV+ (n = 65)	HIV− (n = 18)	AD (n=24)	P
Demographics
Age, years	43 (35; 48)	40 (34; 50)	76.5 (67;79.5)	<0.0001
Education, years	7 (5;11)	12 (11;15.5)	4 (2;6)	0.0001
Gender, n male (%)	32 (49)	14 (77.8)	8 (33)	0.0120
Clinical scales
GDS	0.65 (0.3;1.05)
MMSE	-	-	14 (9.5;20)
MoCA, (n=8)			11.5(10.5;12.5)
FAQ	-	-	23.5 (15;27.5)
Geriatric Depression scale	-	-	1 (0.5;3)
Co-morbidities
HCV, n (%)	10(15)	0	0	-
Log Plasma HCV RNA, n	2.9 (1.7; 5.9)	0	0	-

Data are median (IQR) or number of cases (%).

Hepatitis C virus (HCV) status was assessed by antibody testing (Abbott-Architect).

Participants co-infected with HCV were not on treatment with interferon-gamma.

Mini-mental state examination (MMSE); Montreal Cognitive Assessment (MoCA);

Functional Activities Questionnaire (Pfeffer’s FAQ); Global deficit score (GDS)¹⁸.