Table 2.
Parameters evaluated in the blood of male Wistar rats after exposure to the different treatments after 7 d
| Parameter | Rifampin 8.5 mg/kg (positive control) | H2O (negative control) | C. ternifolia | ||
|---|---|---|---|---|---|
| 8.5 mg/kg | 3.75 mg/kg | 1.25 mg/kg | |||
| WBC (10−3) | 5.0 ± 1.6 | 12.0 ± 1.9 | 4.3 ± 0.3 | 2.5 ± 0.9 | 3.9 ± 1.2 |
| PLT (10−3) | 294.3 ± 24.2 | 900.0 ± 3.9 | 418.0 ± 17.7 | 227 ± 10.2 | 193 ± 5.6 |
| Urea (mg/dL) | 69.5 ± 5.7 | 41.2 ± 5.9 | 57.8 ± 9.0 | ND | ND |
| AST IU | 85.0 ± 2.0 | 34.0 ± 2.3 | 546.0 ± 10.9 | 827 ± 4.7 | 212 ± 1.2 |
| ALT IU | 375.0 ± 1.5 | 50.0 ± 3.5 | 196.0 ± 21.1 | 548 ± 11.5 | 220 ± 9.6 |
| F ALK IU | 376.0 ± 5.0 | 33.0 ± 3.8 | 386.0 ± 5.7 | 697 ± 6.3 | 457 ± 4.9 |
WBC: leukocytes, PLT: platelets, ALT: alanine aminotransferase, AST: aspartate aminotransferase, ALP: alkaline phosphatase, IU: international units, ND: no determinate, and SD: ±. All the treatments have significant difference against the negative control, P=0.01.