Table 3.
Change in patient-reported outcomes by bone graft type
| Variable | BMP-2 (n = 101) | ICBG (n = 48) | p-value† |
|---|---|---|---|
| VAS back | |||
| Preoperative | 6.2 ± 2.5 | 5.9 ± 2.7 | 0.432 |
| 6-Week Δ | -2.2 ± 2.8 | -2.2 ± 3.3 | 0.903 |
| 12-Week Δ | -2.7 ± 2.9 | -3.0 ± 2.5 | 0.555 |
| 6-Month Δ | -2.9 ± 3.1 | -2.8 ± 3.4 | 0.922 |
| 1-Year Δ | -3.2 ± 3.3 | -3.5 ± 3.5 | 0.677 |
| VAS leg | |||
| Preoperative | 5.3 ± 2.7 | 6.1 ± 2.9 | 0.090 |
| 6-Week Δ | -2.4 ± 3.4 | -3.6 ± 3.0 | 0.035* |
| 12-Week Δ | -2.9 ± 2.9 | -4.3 ± 2.9 | 0.014* |
| 6-Month Δ | -3.1 ± 3.0 | -4.0 ± 3.0 | 0.064 |
| 1-Year Δ | -3.2 ± 3.4 | -3.8 ± 3.7 | 0.476 |
| ODI | |||
| Preoperative | 41.0 ± 16.4 | 37.9 ± 17.0 | 0.281 |
| 6-Week Δ | -5.0 ± 19.6 | -8.2 ± 15.8 | 0.339 |
| 12-Week Δ | -12.0 ± 17.4 | -13.0 ± 15.7 | 0.768 |
| 6-Month Δ | -17.4 ± 19.7 | -18.0 ± 17.8 | 0.854 |
| 1-Year Δ | -19.2 ± 18.4 | -20.0 ± 19.1 | 0.843 |
Values are presented as mean±standard deviation.
BMP-2, bone morphogenetic protein-2; ICBG, iliac crest bone graft; VAS, visual analogue scale; ODI, Oswestry Disability Index.
Δ=postoperative ODI/VAS – preoperative ODI/VAS.
*
p<0.05, statistically significant differences.
†
p-values calculated using independent t-tests.