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miR-107 induced cell proliferation and inhibited apoptosis by interplay with PTEN. (A and B) PTEN expression in pcDNA3.1 (NC) or pcDNA-PTEN (PTEN)-transfected C28/I2 cells. (C-H) C28/I2 cells were transiently transfected with miR-NC, miR-107, miR-107+NC, or miR-107+PTEN. At 48 h post-transfection, cell proliferative activity (C), apoptosis (D), as well as Bax, Bcl-2, and Caspase-3 expression (E-H) was detected by MTT, FCM, or WB analysis.
