miR-107 remitted cartilage dysfunction by targeting PTEN. C28/I2 cells were transiently transfected with miR-NC, miR-107, miR-107+NC, or miR-107+PTEN. At 48 h post-transfection, the levels of cartilage matrix-related proteins aggrecan and collagen II, as well as matrix-degrading enzymes MMP-9 and MMP-13 were measured by WB (A-E).